Tuberculosis Epidemiology and Selection in an Autochthonous Siberian Population from the 16th-19th Century
Identifieur interne : 000201 ( Main/Exploration ); précédent : 000200; suivant : 000202Tuberculosis Epidemiology and Selection in an Autochthonous Siberian Population from the 16th-19th Century
Auteurs : Henri Dabernat [France] ; Catherine Thèves [France] ; Caroline Bouakaze [France] ; Dariya Nikolaeva [France] ; Christine Keyser [France] ; Igor Mokrousov [Russie] ; Annie Géraut [France] ; Sylvie Duchesne [France] ; Patrice Gérard [France] ; Anatoly N. Alexeev [Russie] ; Eric Crubézy [France] ; Bertrand Ludes [France]Source :
- PLoS ONE [ 1932-6203 ] ; 2014.
Abstract
Tuberculosis is one of most ancient diseases affecting human populations. Although numerous studies have tried to detect pathogenic DNA in ancient skeletons, the successful identification of ancient tuberculosis strains remains rare. Here, we describe a study of 140 ancient subjects inhumed in Yakutia (Eastern Siberia) during a tuberculosis outbreak, dating from the 16th–19th century. For a long time, Yakut populations had remained isolated from European populations, and it was not until the beginning of the 17th century that first contacts were made with European settlers. Subsequently, tuberculosis spread throughout Yakutia, and the evolution of tuberculosis frequencies can be tracked until the 19th century. This study took a multidisciplinary approach, examining historical and paleo-epidemiological data to understand the impact of tuberculosis on ancient Yakut population. In addition, molecular identification of the ancient tuberculosis strain was realized to elucidate the natural history and host-pathogen co-evolution of human tuberculosis that was present in this population. This was achieved by the molecular detection of the IS
Url:
DOI: 10.1371/journal.pone.0089877
PubMed: 24587092
PubMed Central: 3935942
Affiliations:
- France, Russie
- Midi-Pyrénées, Occitanie (région administrative), Île-de-France
- Paris, Toulouse, Versailles
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>Tuberculosis is one of most ancient diseases affecting human populations. Although numerous studies have tried to detect pathogenic DNA in ancient skeletons, the successful identification of ancient tuberculosis strains remains rare. Here, we describe a study of 140 ancient subjects inhumed in Yakutia (Eastern Siberia) during a tuberculosis outbreak, dating from the 16<sup>th</sup>
–19<sup>th</sup>
century. For a long time, Yakut populations had remained isolated from European populations, and it was not until the beginning of the 17<sup>th</sup>
century that first contacts were made with European settlers. Subsequently, tuberculosis spread throughout Yakutia, and the evolution of tuberculosis frequencies can be tracked until the 19<sup>th</sup>
century. This study took a multidisciplinary approach, examining historical and paleo-epidemiological data to understand the impact of tuberculosis on ancient Yakut population. In addition, molecular identification of the ancient tuberculosis strain was realized to elucidate the natural history and host-pathogen co-evolution of human tuberculosis that was present in this population. This was achieved by the molecular detection of the IS<italic>6110</italic>
sequence and SNP genotyping by the SNaPshot technique. Results demonstrated that the strain belongs to cluster PGG2-SCG-5, evocating a European origin. Our study suggests that the Yakut population may have been shaped by selection pressures, exerted by several illnesses, including tuberculosis, over several centuries. This confirms the validity and necessity of using a multidisciplinary approach to understand the natural history of M<italic>ycobacterium tuberculosis</italic>
infection and disease.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Gagneux, S" uniqKey="Gagneux S">S Gagneux</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stein, Cm" uniqKey="Stein C">CM Stein</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Moller, M" uniqKey="Moller M">M Möller</name>
</author>
<author><name sortKey="De Wit, E" uniqKey="De Wit E">E de Wit</name>
</author>
<author><name sortKey="Hoal, Eg" uniqKey="Hoal E">EG Hoal</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Crubezy, E" uniqKey="Crubezy E">E Crubézy</name>
</author>
<author><name sortKey="Amory, S" uniqKey="Amory S">S Amory</name>
</author>
<author><name sortKey="Keyser, C" uniqKey="Keyser C">C Keyser</name>
</author>
<author><name sortKey="Bouakaze, C" uniqKey="Bouakaze C">C Bouakaze</name>
</author>
<author><name sortKey="Bodner, M" uniqKey="Bodner M">M Bodner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Biagini, P" uniqKey="Biagini P">P Biagini</name>
</author>
<author><name sortKey="Theves, C" uniqKey="Theves C">C Theves</name>
</author>
<author><name sortKey="Balaresque, P" uniqKey="Balaresque P">P Balaresque</name>
</author>
<author><name sortKey="Geraut, A" uniqKey="Geraut A">A Geraut</name>
</author>
<author><name sortKey="Cannet, C" uniqKey="Cannet C">C Cannet</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Theves, C" uniqKey="Theves C">C Thèves</name>
</author>
<author><name sortKey="Senescau, A" uniqKey="Senescau A">A Senescau</name>
</author>
<author><name sortKey="Vanin, S" uniqKey="Vanin S">S Vanin</name>
</author>
<author><name sortKey="Keyser, C" uniqKey="Keyser C">C Keyser</name>
</author>
<author><name sortKey="Ricaut, Fx" uniqKey="Ricaut F">FX Ricaut</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Comas, I" uniqKey="Comas I">I Comas</name>
</author>
<author><name sortKey="Gagneux, S" uniqKey="Gagneux S">S Gagneux</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Dedouit, F" uniqKey="Dedouit F">F Dedouit</name>
</author>
<author><name sortKey="Geraut, A" uniqKey="Geraut A">A Géraut</name>
</author>
<author><name sortKey="Baranov, V" uniqKey="Baranov V">V Baranov</name>
</author>
<author><name sortKey="Ludes, B" uniqKey="Ludes B">B Ludes</name>
</author>
<author><name sortKey="Rouge, D" uniqKey="Rouge D">D Rougé</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="De Vuyst, D" uniqKey="De Vuyst D">D De Vuyst</name>
</author>
<author><name sortKey="Vanhoenacker, F" uniqKey="Vanhoenacker F">F Vanhoenacker</name>
</author>
<author><name sortKey="Gielen, J" uniqKey="Gielen J">J Gielen</name>
</author>
<author><name sortKey="Bernaerts, A" uniqKey="Bernaerts A">A Bernaerts</name>
</author>
<author><name sortKey="De Schepper, Am" uniqKey="De Schepper A">AM De Schepper</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Huang, Ch" uniqKey="Huang C">CH Huang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nathanson, L" uniqKey="Nathanson L">L Nathanson</name>
</author>
<author><name sortKey="Cohen, W" uniqKey="Cohen W">W Cohen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rasool, Mn" uniqKey="Rasool M">MN Rasool</name>
</author>
<author><name sortKey="Govender, S" uniqKey="Govender S">S Govender</name>
</author>
<author><name sortKey="Naidoo, Ks" uniqKey="Naidoo K">KS Naidoo</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Teo, Hel" uniqKey="Teo H">HEL Teo</name>
</author>
<author><name sortKey="Peh, Wcg" uniqKey="Peh W">WCG Peh</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Keyser Tracqui, C" uniqKey="Keyser Tracqui C">C Keyser-Tracqui</name>
</author>
<author><name sortKey="Ludes, B" uniqKey="Ludes B">B Ludes</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mendisco, F" uniqKey="Mendisco F">F Mendisco</name>
</author>
<author><name sortKey="Keyser, C" uniqKey="Keyser C">C Keyser</name>
</author>
<author><name sortKey="Hollard, C" uniqKey="Hollard C">C Hollard</name>
</author>
<author><name sortKey="Seldes, V" uniqKey="Seldes V">V Seldes</name>
</author>
<author><name sortKey="Nielsen, A" uniqKey="Nielsen A">A Nielsen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Fletcher, Ha" uniqKey="Fletcher H">HA Fletcher</name>
</author>
<author><name sortKey="Donoghue, Hd" uniqKey="Donoghue H">HD Donoghue</name>
</author>
<author><name sortKey="Taylor, Gm" uniqKey="Taylor G">GM Taylor</name>
</author>
<author><name sortKey="Van Der Zanden, Ag" uniqKey="Van Der Zanden A">AG van der Zanden</name>
</author>
<author><name sortKey="Spigelman, M" uniqKey="Spigelman M">M Spigelman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Taylor, G" uniqKey="Taylor G">G Taylor</name>
</author>
<author><name sortKey="Crossey, M" uniqKey="Crossey M">M Crossey</name>
</author>
<author><name sortKey="Saldanha, J" uniqKey="Saldanha J">J Saldanha</name>
</author>
<author><name sortKey="Waldron, T" uniqKey="Waldron T">T Waldron</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sreevatsan, S" uniqKey="Sreevatsan S">S Sreevatsan</name>
</author>
<author><name sortKey="Pan, X" uniqKey="Pan X">X Pan</name>
</author>
<author><name sortKey="Stockbauer, Ke" uniqKey="Stockbauer K">KE Stockbauer</name>
</author>
<author><name sortKey="Connel, Nd" uniqKey="Connel N">ND Connel</name>
</author>
<author><name sortKey="Kreisswirth, Bn" uniqKey="Kreisswirth B">BN Kreisswirth</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Grigg, Er" uniqKey="Grigg E">ER Grigg</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Aparicio, J" uniqKey="Aparicio J">J Aparicio</name>
</author>
<author><name sortKey="Castillo Chavez, C" uniqKey="Castillo Chavez C">C Castillo-Chavez</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Ussery, Xt" uniqKey="Ussery X">XT Ussery</name>
</author>
<author><name sortKey="Valway, Se" uniqKey="Valway S">SE Valway</name>
</author>
<author><name sortKey="Mckenna, M" uniqKey="Mckenna M">M McKenna</name>
</author>
<author><name sortKey="Cauthen, Gm" uniqKey="Cauthen G">GM Cauthen</name>
</author>
<author><name sortKey="Mccray, E" uniqKey="Mccray E">E McCray</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Walls, T" uniqKey="Walls T">T Walls</name>
</author>
<author><name sortKey="Shingadia, D" uniqKey="Shingadia D">D Shingadia</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Myglan, Vs" uniqKey="Myglan V">VS Myglan</name>
</author>
<author><name sortKey="Vaganov, Ea" uniqKey="Vaganov E">EA Vaganov</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Bates, Jh" uniqKey="Bates J">JH Bates</name>
</author>
<author><name sortKey="Stead, Ww" uniqKey="Stead W">WW Stead</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Suzuki, T" uniqKey="Suzuki T">T Suzuki</name>
</author>
<author><name sortKey="Inoue, T" uniqKey="Inoue T">T Inoue</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Dabernat, H" uniqKey="Dabernat H">H Dabernat</name>
</author>
<author><name sortKey="Reis, Tm" uniqKey="Reis T">TM Reis</name>
</author>
<author><name sortKey="Tarasov A, Y" uniqKey="Tarasov A Y">Y Tarasov A</name>
</author>
<author><name sortKey="Artyukhov, Ip" uniqKey="Artyukhov I">IP Artyukhov</name>
</author>
<author><name sortKey="Nikolaev, Vg" uniqKey="Nikolaev V">VG Nikolaev</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Alcais, A" uniqKey="Alcais A">A Alcaïs</name>
</author>
<author><name sortKey="Fieschi, C" uniqKey="Fieschi C">C Fieschi</name>
</author>
<author><name sortKey="Abel, L" uniqKey="Abel L">L Abel</name>
</author>
<author><name sortKey="Casanova, J" uniqKey="Casanova J">J Casanova</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Demay, C" uniqKey="Demay C">C Demay</name>
</author>
<author><name sortKey="Liens, B" uniqKey="Liens B">B Liens</name>
</author>
<author><name sortKey="Burguiere, T" uniqKey="Burguiere T">T Burguière</name>
</author>
<author><name sortKey="Hill, V" uniqKey="Hill V">V Hill</name>
</author>
<author><name sortKey="Couvin, D" uniqKey="Couvin D">D Couvin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Filliol, I" uniqKey="Filliol I">I Filliol</name>
</author>
<author><name sortKey="Motiwala, As" uniqKey="Motiwala A">AS Motiwala</name>
</author>
<author><name sortKey="Cavatore, M" uniqKey="Cavatore M">M Cavatore</name>
</author>
<author><name sortKey="Qi, W" uniqKey="Qi W">W Qi</name>
</author>
<author><name sortKey="Hazb N, Mh" uniqKey="Hazb N M">MH Hazbón</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gagneux, S" uniqKey="Gagneux S">S Gagneux</name>
</author>
<author><name sortKey="Deriemer, K" uniqKey="Deriemer K">K DeRiemer</name>
</author>
<author><name sortKey="Van, T" uniqKey="Van T">T Van</name>
</author>
<author><name sortKey="Kato Maeda, M" uniqKey="Kato Maeda M">M Kato-Maeda</name>
</author>
<author><name sortKey="De Jong, Bc" uniqKey="De Jong B">BC de Jong</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gutacker, Mm" uniqKey="Gutacker M">MM Gutacker</name>
</author>
<author><name sortKey="Mathema, B" uniqKey="Mathema B">B Mathema</name>
</author>
<author><name sortKey="Soini, H" uniqKey="Soini H">H Soini</name>
</author>
<author><name sortKey="Shashkina, E" uniqKey="Shashkina E">E Shashkina</name>
</author>
<author><name sortKey="Kreiswirth, Bn" uniqKey="Kreiswirth B">BN Kreiswirth</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hershberg, R" uniqKey="Hershberg R">R Hershberg</name>
</author>
<author><name sortKey="Lipatov, M" uniqKey="Lipatov M">M Lipatov</name>
</author>
<author><name sortKey="Small, Pm" uniqKey="Small P">PM Small</name>
</author>
<author><name sortKey="Sheffer, H" uniqKey="Sheffer H">H Sheffer</name>
</author>
<author><name sortKey="Niemann, S" uniqKey="Niemann S">S Niemann</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Mokrousov, I" uniqKey="Mokrousov I">I Mokrousov</name>
</author>
<author><name sortKey="Ly, Hm" uniqKey="Ly H">HM Ly</name>
</author>
<author><name sortKey="Otten, T" uniqKey="Otten T">T Otten</name>
</author>
<author><name sortKey="Lan, Nn" uniqKey="Lan N">NN Lan</name>
</author>
<author><name sortKey="Vyshnevskyi, B" uniqKey="Vyshnevskyi B">B Vyshnevskyi</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Sinkov, Vv" uniqKey="Sinkov V">VV Sinkov</name>
</author>
<author><name sortKey="Savilov, Ed" uniqKey="Savilov E">ED Savilov</name>
</author>
<author><name sortKey="Ogarkov, Ob" uniqKey="Ogarkov O">OB Ogarkov</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Thorne, N" uniqKey="Thorne N">N Thorne</name>
</author>
<author><name sortKey="Borrell, S" uniqKey="Borrell S">S Borrell</name>
</author>
<author><name sortKey="Evans, J" uniqKey="Evans J">J Evans</name>
</author>
<author><name sortKey="Magee, J" uniqKey="Magee J">J Magee</name>
</author>
<author><name sortKey="De Viedma, Dg" uniqKey="De Viedma D">DG de Viedma</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wirth, T" uniqKey="Wirth T">T Wirth</name>
</author>
<author><name sortKey="Hildebrand, F" uniqKey="Hildebrand F">F Hildebrand</name>
</author>
<author><name sortKey="Allix Beguec, C" uniqKey="Allix Beguec C">C Allix-Béguec</name>
</author>
<author><name sortKey="Wolbeling, F" uniqKey="Wolbeling F">F Wölbeling</name>
</author>
<author><name sortKey="Kubica, T" uniqKey="Kubica T">T Kubica</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zhdanova, S" uniqKey="Zhdanova S">S Zhdanova</name>
</author>
<author><name sortKey="Heysell, Sk" uniqKey="Heysell S">SK Heysell</name>
</author>
<author><name sortKey="Ogarkov, O" uniqKey="Ogarkov O">O Ogarkov</name>
</author>
<author><name sortKey="Boyarinova, G" uniqKey="Boyarinova G">G Boyarinova</name>
</author>
<author><name sortKey="Alexeeva, G" uniqKey="Alexeeva G">G Alexeeva</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Dymova, M" uniqKey="Dymova M">M Dymova</name>
</author>
<author><name sortKey="Kinsht, V" uniqKey="Kinsht V">V Kinsht</name>
</author>
<author><name sortKey="Cherednichenko, A" uniqKey="Cherednichenko A">A Cherednichenko</name>
</author>
<author><name sortKey="Khrapov, E" uniqKey="Khrapov E">E Khrapov</name>
</author>
<author><name sortKey="Svistelnik, A" uniqKey="Svistelnik A">A Svistelnik</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Matrakshin, A" uniqKey="Matrakshin A">A Matrakshin</name>
</author>
<author><name sortKey="Mes Ko, E" uniqKey="Mes Ko E">E Mes'ko</name>
</author>
<author><name sortKey="Nk, B" uniqKey="Nk B">B NK</name>
</author>
<author><name sortKey="Andreevskaia, S" uniqKey="Andreevskaia S">S Andreevskaia</name>
</author>
<author><name sortKey="Smirnova, T" uniqKey="Smirnova T">T Smirnova</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chan, J" uniqKey="Chan J">J Chan</name>
</author>
<author><name sortKey="Sergeant, M" uniqKey="Sergeant M">M Sergeant</name>
</author>
<author><name sortKey="Lee, O" uniqKey="Lee O">O Lee</name>
</author>
<author><name sortKey="Minnikin, D" uniqKey="Minnikin D">D Minnikin</name>
</author>
<author><name sortKey="Besra, G" uniqKey="Besra G">G Besra</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations><list><country><li>France</li>
<li>Russie</li>
</country>
<region><li>Midi-Pyrénées</li>
<li>Occitanie (région administrative)</li>
<li>Île-de-France</li>
</region>
<settlement><li>Paris</li>
<li>Toulouse</li>
<li>Versailles</li>
</settlement>
</list>
<tree><country name="France"><region name="Occitanie (région administrative)"><name sortKey="Dabernat, Henri" sort="Dabernat, Henri" uniqKey="Dabernat H" first="Henri" last="Dabernat">Henri Dabernat</name>
</region>
<name sortKey="Bouakaze, Caroline" sort="Bouakaze, Caroline" uniqKey="Bouakaze C" first="Caroline" last="Bouakaze">Caroline Bouakaze</name>
<name sortKey="Crubezy, Eric" sort="Crubezy, Eric" uniqKey="Crubezy E" first="Eric" last="Crubézy">Eric Crubézy</name>
<name sortKey="Duchesne, Sylvie" sort="Duchesne, Sylvie" uniqKey="Duchesne S" first="Sylvie" last="Duchesne">Sylvie Duchesne</name>
<name sortKey="Gerard, Patrice" sort="Gerard, Patrice" uniqKey="Gerard P" first="Patrice" last="Gérard">Patrice Gérard</name>
<name sortKey="Geraut, Annie" sort="Geraut, Annie" uniqKey="Geraut A" first="Annie" last="Géraut">Annie Géraut</name>
<name sortKey="Keyser, Christine" sort="Keyser, Christine" uniqKey="Keyser C" first="Christine" last="Keyser">Christine Keyser</name>
<name sortKey="Ludes, Bertrand" sort="Ludes, Bertrand" uniqKey="Ludes B" first="Bertrand" last="Ludes">Bertrand Ludes</name>
<name sortKey="Ludes, Bertrand" sort="Ludes, Bertrand" uniqKey="Ludes B" first="Bertrand" last="Ludes">Bertrand Ludes</name>
<name sortKey="Nikolaeva, Dariya" sort="Nikolaeva, Dariya" uniqKey="Nikolaeva D" first="Dariya" last="Nikolaeva">Dariya Nikolaeva</name>
<name sortKey="Theves, Catherine" sort="Theves, Catherine" uniqKey="Theves C" first="Catherine" last="Thèves">Catherine Thèves</name>
</country>
<country name="Russie"><noRegion><name sortKey="Mokrousov, Igor" sort="Mokrousov, Igor" uniqKey="Mokrousov I" first="Igor" last="Mokrousov">Igor Mokrousov</name>
</noRegion>
<name sortKey="Alexeev, Anatoly N" sort="Alexeev, Anatoly N" uniqKey="Alexeev A" first="Anatoly N." last="Alexeev">Anatoly N. Alexeev</name>
</country>
</tree>
</affiliations>
</record>
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